Cytarabine hydrochloride
Product Name: Cytarabine hydrochloride
Specification: 99.5% min
Appearance: Small white needle crystal or crystal powder
CAS No.: 69-74-9
Package: For minimal order: 1KG/Aluminium foil bag, 5 bags in a carton . For large quantity: 25KG/Fiber Drum in net weight; 28KG/Fiber Drum in gross weight (Can be customized)

Products Description:

1. Cytarabine hydrochloride is an anti-leukemic agent which binds to topoisomerase I, resulting in DNA fragmentation and inhibition of replication.

2. This compound does not have any effects on RNA synthesis.

3. Studies suggest that cytosine β-D-arabinofuranoside hydrochloride can down-regulate deoxycytidine kinase in acute myeloid leukemia murine cell lines, which inhibits the phosphorylation of several deoxyribonucleosides.

4. Cytosine β-D-arabinofuranoside hydrochloride can be inhibited in myeloid leukemic cells via suppression of ENT1 promoter activity, responsible for transporting cytosine β-D-arabinofuranoside into the cell.
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